Sculpting synthetic cell membranes with co-transcriptional RNA condensates (DC17)
About the project With this project, we aim to engineer interactions between the synthetic RNA condensates and synthetic cell membranes […]
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Dynamic polymeric synthetic cells: design, fusion, and condensate control for enhanced membrane behaviours (DC16)
About the project This research project aims to advance synthetic cell technology by developing synthetic constructs that mimic the structural
Light-controlled interactions between membrane and biomolecular condensates in artificial cells (DC15)
About the project The group has recently intercalated a photo-switchable amphiphilic molecule into the phospholipid scaffold of an artificial cell
How can membranes control condensate formation and location? (DC14)
About the project The Sorkin Lab has extensive experience in studying membrane remodelling processes using mechanical single-molecule techniques. In this
Photo-regulation of the interactions between membranes and protein condensates (DC13)
About the project We will study the influence of lipid oxidation on the ability of the membranes to interact with
In silico membrane reshaping by molecular condensates (DC12)
About the project In this project we will build a coarse-grained Molecular Dynamics (MD) model of molecular condensates in contact
Active membrane expansion with condensates (DC11)
About the project The project aims to implement lipid translocases to flip lipids from the inner to the outer leaflet or
Peptide protofilament interactions with polymeric membranes and RNA condensates (DC10)
About the project This project focuses on synthetic peptide scaffolds and their ability to form functional protofilaments under confined conditions.
Synthetic peptide scaffolds as functional protofilaments under confinement (DC09)
About the project This project focuses on synthetic peptide scaffolds and their ability to form functional protofilaments under confined conditions.
Phase-separated condensation of energy-dissipating self-organizing protein systems in crowded cell-like membrane containers (DC08)
About the project The project aims to decipher how the physicochemical elements of the local intracellular environments (namely macromolecular crowding,